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Businesses for Sale in Port St. Lucie, FL

The Treasure Coast's largest and fastest-growing city. Every business currently for sale in Port St. Lucie, straight from the MLS and updated throughout the day.

Port St. Lucie is the largest city on the Treasure Coast and one of Florida's fastest-growing, with commercial growth along US-1, St. Lucie West Boulevard and Tradition. Businesses for sale here include restaurants, service businesses and retail at prices well below South Florida's coastal cities.

Port St. Lucie Businesses for Sale: The Numbers

For sale now4
Median asking price—
Median gross revenue (1 listings report it)—
Median net income (0 listings report it)—
Listed in the last 30 days3
Price reduced since listing0
Seller financing offered2

Source: MLS business opportunity listings, every active listing on this page asking $240,000 or more as of November 8, 2026. These are asking prices, not sale prices, and gross and net income as the listing agents report them. A median of fewer than 5 listings is shown as —.

Before You Buy: The Acquisition Guides

4 listings, newest first.

Businesses for Sale in Port St. Lucie, FL: Questions

How many businesses are for sale in Port St. Lucie, FL?
4 businesses were listed for sale in Port St. Lucie, FL as of November 8, 2026. 3 came on the market in the last 30 days and 2 offer seller financing. The figures come from the MLS and update through the day.
What kinds of businesses are for sale in Port St. Lucie, FL?
The largest groups right now are service businesses (2), franchises (1), retail businesses (1). Port St.

Thinking about selling a business in Port St. Lucie?

Your buyer may already be looking for an opportunity like yours. Speak with a BreakThru Realty business broker about your goals and a confidential strategy for reaching potential buyers, with a valuation from recent sales of comparable businesses, no listing and no obligation. Discuss My Business Sale.

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