Businesses for Sale in Port St. Lucie, FL

The Treasure Coast's largest and fastest-growing city. Every business currently for sale in Port St. Lucie, straight from the MLS and updated throughout the day.

Port St. Lucie is the largest city on the Treasure Coast and one of Florida's fastest-growing, with commercial growth along US-1, St. Lucie West Boulevard and Tradition. Businesses for sale here include restaurants, service businesses and retail at prices well below South Florida's coastal cities.

9 listings, newest first.

Thinking about selling a business in Port St. Lucie?

Buyers on this page are looking for a business like yours. Get a confidential valuation from recent sales of comparable businesses, with no listing and no obligation. Request a confidential business valuation.

Businesses for Sale By Industry

Businesses for Sale By Asking Price

Businesses for Sale By Terms

Businesses for Sale By County

Businesses for Sale By City

Explore